Pemanfaatan Precipitated Calcium Carbonat dari Batu Kapur dalam Pembuatan β-TCP sebagai Bahan Dasar Implan Tulang

Noor Isnaini Azkiya, Fanny Prasetia, Rosita Dwi Chrisnandari, Wianthi Septia Witasari

Abstract


Salah satu material yang bersifat biokompatibel serta sering digunakan sebagai bahan dasar implan tulang dan gigi adalah trikalsium fosfat. Material ini dapat dihasilkan dari precipitated calcium carbonate (PCC) batu kapur karena memiliki kandungan kalsium yang sangat tinggi. Metode yang digunakan untuk mensintesis trikalsium fosfat yaitu melalui pengendapan prekursor CaO dan H3PO4 dalam media etanol. Hasil sintesis dikarakterisasi menggunakan instrumen FT-IR, AAS, spektroskopi UV-Vis, dan XRD. Dari hasil analisis spektroskopi UV-Vis, rasio Ca/P dari hasil sintesis diperoleh sebesar 1,64. Uji FT-IR menunjukkan adanya gugus Ca-O pada bilangan gelombang sekitar 1400 cm-1 dan gugus PO43- pada bilangan gelombang 561 cm-1 dan 1041 cm-1. Uji XRD menunjukkan 3 puncak tertinggi dari β-TCP (trikalsium fosfat) yang sesuai dengan JCPDS no. 09-0169.

One of the biocompatible materials that are often used as a basic materials for bone and dental implants is tricalcium phosphate. This material can be produced from precipitated calcium carbonate (PCC) limestone because it has a very high calcium content. The method used to synthesize tricalcium phosphate was deposition of CaO and H3PO4 precursors in ethanol media. The results of the synthesis was characterized using FT-IR instruments, AAS, UV-Vis spectroscopy, and XRD. Based on the results of the UV-Vis spectroscopic analysis, the Ca/P ratio of the synthesis results obtained was 1.87. FT-IR test showed the presence of a Ca-O group at wave number 1400 cm-1 and PO43- group at wave numbers 561 cm-1 and 1041 cm-1. XRD test showed highest peaks of β-TCP (tricalcium phosphate) according to JCPDS no. 09-0169.


Keywords


limestone; PCC; tricalcium phosphate; bone implants

Full Text:

PDF

References


N. F. Apriliani, M. A. Baqiya, Darminto, Pengaruh Penambahan Larutan MgCl2 pada Sintesis Kalsium Karbonat Presipitat Berbahan Dasar Batu Kapur dengan Metode Karbonasi, Jurnal Sains dan Seni ITS, vol. 1, no. 1, hal. B-30-B-34, 2012.

D. W. Nurhajati, S. Brotoningsih, Pengaruh Nano-Precipitated Calcium Carbonate Terhadap Kualitas Komposit Polivinil Klorida, Jurnal Riset Industri, vol. 6, no. 2, hal. 13-20, 2012.

P. Sabriye, D. O. Ozgul, Effect of Process Conditions on Crystal Structure of Precipitated Calcium Carbonate (CaCO3) from Fly Ash: Na2CO3 Preparation Conditions, International Journal of Chemical, Environmental and Biological Sciences, vol. 1, no. 6, hal. 192-195, 2012.

J.-A. Kim, G.-C. Han, M. Lim, K.-S. You, M. Ryu, J.-W. Ahn, T. Fujita, H. Kim, Effect of Hydraulic Activity on Crystallization of Precipitated Calcium Carbonate (PCC) for Eco-Friendly Paper, International Journal of Molecular Sciences, vol. 10, no. 11, hal. 4954-4962, 2009.

K. Dahlan, Y. W. Sari, E. Yuniarti, D.S. Soejoko, Karakterisasi Gugus Fosfat dan Karbonat dalam Tulang Tikus dengan Fourier Transform Infrared (FT-IR) Spectroscopy, Jurnal Sains Material Indonesia, hal. 221-224, 2006.

J. Sedyono, A. E. Tontowi, Proses Sintesis dan Karakterisasi FTIR Hidroksiapatit dari Gipsum Alam Kulon Progo, Media Mesin: Majalah Teknik Mesin, vol. 9, no. 1, hal. 6-12, 2008.

L. Wang, G. H. Nancollas, Calcium Orthophosphates: Crystallization and Dissolution, Chemical Reviews, vol. 108, no. 11, hal. 4628-4669, 2008.

S. V. Dorozhkin, Calcium Ortho-phosphates as Bioceramics: State of the Art, Journal of Functional Biomaterials, vol. 1, no.1, hal. 22-107, 2010.

J. Van der Stock, E. M. M. Van Lieshout, Y. El-Massoudi, G. H. Van Kralingen, P. Patka, Bone Subtitutes in the Netherlands – A Systematic literatur review, Acta Biomaterialia, vol. 7, no. 2, hal. 739-750, 2011.

Q. Lailiyah, M. A. Baqiya, Darminto, Pengaruh Temperatur dan Laju Aliran Gas CO2 pada Sintesis Kalsium Karbonat Presipitat dengan Metode Bubbling, Jurnal Sains dan Seni ITS, vol. 1, no. 1, hal. B-6-B-10, 2012.

I. Wahdah, S. Wardhani, Darjito, Sintesis Hidroksiapatit dari Tulang Sapi dengan Metode Basah-Pengendapan, Kimia Student Journal, vol. 1, no. 1, hal. 92-97, 2014.

Z. R. Zhang, The Use of Precipitated Calcium Carbonate as TiO2 Extender in Architectural Flat Wall Paint, Mississippi Lime Company, Ste. Genevieve, MO63670.

R. A. Nyquist, R. O. Kagel, Infrared Spectra of Inorganic Compound, Acadenic Press, Inc.: London, 1971.

M. D. Vlad, S. Gómez, M. Barracó, J. López, E. Fernández, Effect of the Calcium to Phosphorus Ratio on the Setting Properties of Calcium Phosphate Bone Cements, Journal Materials Science: Materials in Medicine, vol. 23, hal. 2081-2090, 2012.




DOI: http://dx.doi.org/10.33795/jtkl.v5i1.208

Refbacks

  • There are currently no refbacks.


Copyright (c) 2021 Noor Isnaini Azkiya, Fanny Prasetia, Rosita Dwi Chrisnandari, Wianthi Septia Witasari

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.